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Search Results for " cell division cycle 37 "

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抑制剂 & 化合物

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重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T36197	CAY10747
	CAY10747 is an inhibitor of the protein-protein interaction between heat shock protein 90 (Hsp90) and cell division cycle 37 (Cdc37) and a derivative of celastrol .1It decreases protein levels of the Hsp90-Cdc37 complex and the Hsp90-Cdc37 clients phosphorylated Akt and Cdk4 in A549 cells when used at a concentration of 5 μM. CAY10747 inhibits proliferation of A549, MCF-7, HOS, and HepG2 cells (IC50s = 0.41, 0.64, 0.9, and 0.94 μM, respectively) and induces apoptosis in A549 cells. 1.Li, N., Xu,...

化合物

Cat.No: T36197

Species：

Expression System：

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Cat. No.	Product Name	Species	Expression System
TMPY-01715	CDC37 Protein, Human, Recombinant (GST) cell division cycle 37,P...	Human	Baculovirus-Insect Cells
	CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is thought to play an important role in the establishment of signaling pathways controlling cell proliferation through targeting intrinsically unstable oncoprotein kinases such as Cdk-4, Raf-1, and src to the molecular chaperone Hsp90. Decreased Hsp90 expression can reduce the leve...
TMPY-03558	CDC37 Protein, Mouse, Recombinant p50Cdc37,cell division cycle<...	Mouse	Baculovirus-Insect Cells
	CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is thought to play an important role in the establishment of signaling pathways controlling cell proliferation through targeting intrinsically unstable oncoprotein kinases such as Cdk-4, Raf-1, and src to the molecular chaperone Hsp90. Decreased Hsp90 expression can reduce the leve...
TMPY-03534	CDC37 Protein, Mouse, Recombinant (His & GST) cell division cycle 37,p...	Mouse	Baculovirus-Insect Cells
	CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is thought to play an important role in the establishment of signaling pathways controlling cell proliferation through targeting intrinsically unstable oncoprotein kinases such as Cdk-4, Raf-1, and src to the molecular chaperone Hsp90. Decreased Hsp90 expression can reduce the leve...

重组蛋白

CDC37 Protein, Human, Recombinant (GST)

Cat.No: TMPY-01715

Species: Human

Expression System: Baculovirus-Insect Cells

CDC37 Protein, Mouse, Recombinant

Cat.No: TMPY-03558

Species: Mouse

Expression System: Baculovirus-Insect Cells

CDC37 Protein, Mouse, Recombinant (His & GST)

Cat.No: TMPY-03534

Species: Mouse

Expression System: Baculovirus-Insect Cells

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